Research Project
Computational modeling for HCV vaccine trial design and optimal vaccine-based combination interventions
- Principal Investigator
- Boodram, Basmattee
- Start Date
- 2021-11-01
- End Date
- 2026-10-31
- Research Area(s)
- Infectious Diseases
- Funding Source
- NIH/ Loyola University R01AI158666
Abstract
We propose to develop comprehensive, empirical, data-driven agent-based models for persons who inject drugs (PWID) using Chicago and San Francisco PWID populations, contrasting geographies for high and low hepatitis C incidence. The models would assist hepatitis C vaccine-trial sponsors in designing and evaluating clinical trials and enable policy makers to identify the most effective vaccine-based combination intervention strategies for elimination of hepatitis C that includes direct-acting antivirals and engagement in harm reduction such as medications for opioid use disorder and syringe service programs. View sponsor listing